He aha ka Wheat Germ Extract Spermidine?

Ka ʻepekema Ma hope o Spermidine

ʻO Spermidine kahi polyamine kūlohelohe e hana nui ana i nā kaʻina hana kelepona. ʻO nā polyamines, e like me ka spermidine, he mea koʻikoʻi no ka ulu ʻana, ka hana hou ʻana, a me ka mālama ʻana i nā cell. Hoʻopili nui kēia mau pūhui i ka hoʻoponopono ʻana i ka autophagy, ke kaʻina hana e hoʻihoʻi hou ai ke kino a hoʻomaʻemaʻe i nā cell i pōʻino. ʻO kēia ʻano hana "hale mālama" kūloko ke kikowaena o ke olakino a ke hoʻopili ʻia nei i ka emi ʻana o ka makahiki.

Nā hopena kūʻē i ka wā kahiko:Ua hoʻopili ʻia ʻo Spermidine i nā hopena anti-aging, no ka mea, ua ʻike ʻia ua hoʻemi ʻia i nā pae me ka ʻelemakule a pili pū me ka pōkole o ke ola a me nā maʻi he nui, e like me ka pale ʻana i ka immune, nā maʻi inflammatory, nā pilikia cardiovascular a i ʻole nā ​​​​pūnaewele, a me ka tumorigenesis.
Ka hana o ke kino:He kuleana koʻikoʻi ka Spermidine i ka hana o ka cell immune, me ka hoʻokaʻawale ʻana a me ka mālama ʻana o nā cell T, B cell, a me nā cell killer natural (NK). Hāʻawi pū ia i ka polarization o nā macrophages i kahi phenotype anti-inflammatory, no laila e kōkua ai i ka hoʻēmi ʻana i ka mumū.
Ka pilina me Gut Microbiota:Hōʻike nā hōʻike e hiki i ka ʻōpū microbiota ke synthesize spermidine mai nā polyamines ʻē aʻe a i ʻole nā ​​​​mea mua. Hiki i kēia pilina ma waena o ka bacteria a me ka host ke hoʻololi i nā pae spermidine o ka host a me ke olakino holoʻokoʻa.
Ka pale ʻana i ka maʻi cardiovascular:Ua hōʻike ʻo Spermidine i nā hopena cardioprotective, hiki ke kōkua i ka pale ʻana i nā maʻi cardiovascular.
Neuroprotection: Ua hōʻike pū kekahi i nā hopena neuroprotective, hiki ke kōkua i ka hakakā ʻana i nā maʻi neurodegenerative.
Kāohi i ka maʻi maʻi:Ma ka hoʻoulu ʻana i ka immunosurveillance anticancer, hiki i ka spermidine ke kōkua i ka pale ʻana i ka maʻi kanesa.
Hoʻoponopono Metabolic: Hoʻopili ʻo Spermidine i ka hoʻoponopono metabolic o polyamines, e komo pū ana ka pilina ma waena o ka mea hoʻokipa a me kāna microbiota.
Nā hoʻokolohua lapaʻau a me ka palekana:No ka mea, aia maoli ka spermidine i loko o ka meaʻai kanaka, ua manaʻo ʻia nā hoʻokolohua lapaʻau e hoʻonui i kona uptake. Ua mālama ʻia ka noiʻi e loiloi i ka palekana o ka spermidine, nā hopena olakino, absorption, metabolism, a me ka bioprocessing.
I ka hopena, ʻo ka spermidine he mole multifaceted me nā hopena kūpono no ke olakino o ke kanaka, me ka anti-aging, immune function, a me ka pale ʻana i nā maʻi like ʻole. ʻO kāna mau hana e pili ana i ka launa pū ʻana me ka microbiota gut, nā cell immune, a me nā ala metabolic. ʻO nā noiʻi hou aʻe a me nā hoʻokolohua lapaʻau e ʻimi paha i kona hiki ke lilo i mea lapaʻau.

ʻO ka moʻolelo meaʻai o ka hua palaoa

ʻO ka huapalaoa, ka ʻāpana hānau o ka palaoa, he waiwai nui ka meaʻai. Loaʻa iā ia ka nui o ka vitamin E, magnesium, zinc, a me ka fiber. Eia naʻe, ʻo ka mea i ʻoi aku ka maikaʻi o ka hua palaoa ʻo kona ʻano spermidine. ʻOiai aia nā liʻiliʻi o ka spermidine i nā kumu meaʻai like ʻole, hāʻawi ka hua palaoa i kahi ʻano paʻa a maʻalahi.

Polokina:He kumu maikaʻi ʻo Wheat germ no ka protein, nona nā ʻakika amino koʻikoʻi ʻewalu, e lilo ia i kumu protein piha.
Uila:Loaʻa iā ia ka fiber soluble a me ka insoluble, kahi e kōkua ai i ka ʻai ʻana a kōkua i ka hoʻoponopono ʻana i nā pae kō koko.
Vitamin E:ʻO ka huapalaoa kekahi o nā kumu waiwai nui o ka huaora E, ʻo ia hoʻi ke ʻano tocopherol, he antioxidant ikaika.
ʻO nā huaora B:He kumu waiwai ia o nā huaora B, me ka thiamin (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), pyridoxine (B6), a me ka folate (B9). He kuleana koʻikoʻi kēia mau huaora i ka hana ʻana o ka ikehu a me ka hoʻokumu ʻana o ke koko ʻulaʻula.
Vitamin B12:ʻOiai ʻaʻole i loaʻa maʻamau i nā meaʻai mea kanu, ʻo ka hua palaoa kekahi o nā kumu mea kanu liʻiliʻi o ka huaora B12, he mea nui ia no ka hana aʻalolo a me ka hana ʻana o DNA a me RNA.
Nā ʻakika momona:Loaʻa i ka hua huapalaoa kahi koena maikaʻi o nā momona monounsaturated a me nā momona polyunsaturated, me ka omega-3 a me ka omega-6 fatty acids, he mea nui ia no ke olakino naʻau.
Nā mea minelala:He kumu ia o nā minela like ʻole e like me ka magnesium, phosphorus, potassium, zinc, iron, a me selenium, he mea nui ia no nā hana kino he nui.
Nā Phytosterols:Aia i loko o ka huapalaoa nā phytosterols, nā mea kanu e kōkua i ka hoʻohaʻahaʻa i nā pae cholesterol.
ʻO nā antioxidants:Ma waho aʻe o ka huaora E, loaʻa i ka hua palaoa nā antioxidants e kōkua i ka pale ʻana i nā cell mai ka pōʻino i hoʻokumu ʻia e nā radical manuahi.
Nā kalapona:Hāʻawi ʻo ia i nā haʻahaʻa paʻakikī, kahi i hoʻokahe mālie ʻia a hāʻawi i kahi kumu paʻa o ka ikehu.
Hiki ke hoʻohana ʻia ka hua huapalaoa ma nā ʻano like ʻole, e like me ka mea hoʻohui i ka smoothies, kāpīpī ʻia ma ka cereals, a i ʻole he mea hoʻohui i loko o nā meaʻai i kālua ʻia. Ma muli o ka nui o ka momona, hiki ke lilo i rancid inā ʻaʻole mālama pono ʻia, no laila he mea nui e mālama ʻia i loko o ka pahu hau a i ʻole ka hau e mālama ai i kona ʻano hou a me ka waiwai meaʻai.

 

Pehea e hana ai ka spermidine o ka hua palaoa

Ke hoʻopau ʻia, hoʻomoʻa ʻia ka spermidine mai ka palaoa germ extract a hoʻomaka i kāna hana i nā kaʻina kelepona. ʻO kekahi o kāna mau hana mua ka hoʻonui ʻana i ka hana mitochondrial. ʻO Mitochondria, i wehewehe pinepine ʻia e like me nā "mana" o ke kelepona, ke kuleana no ka hana ʻana i ka ikehu. Ma ke kākoʻo ʻana i ka hana mitochondrial, ʻaʻole kōkua wale ka spermidine i ka hana ʻana i ka ikehu akā kōkua pū kekahi i ka hōʻemi ʻana i ke kaumaha oxidative, kahi kumu nui i ka ʻelemakule. Penei ka hana ana i loko o ke kino:

Autophagy Induction:ʻO kekahi o nā hana koʻikoʻi i manaʻo ʻia e kōkua ka spermidine i ke olakino a me ka lōʻihi o ke ola ʻana ma o ka hoʻoulu ʻana o ka autophagy, kahi kaʻina cellular e pili ana i ka hoʻohaʻahaʻa ʻana a me ka hana hou ʻana o nā ʻāpana cellular i pōʻino. Hoʻopili ʻia kēia kaʻina hana me ka hoʻomaʻemaʻe ʻana i nā organelles i hōʻino ʻia a me nā aggregates protein, hiki ke hōʻiliʻili me ka makahiki a kōkua i nā maʻi like ʻole. Ma ka hoʻolaha ʻana i ka autophagy, hiki i ka spermidine ke kōkua i ka mālama ʻana i ke olakino a me ka hana.

Hoʻoponopono o Gene Expression:Ua hōʻike ʻia ʻo Spermidine e pili ana i ke kūlana acetylation o nā histones a me nā protein ʻē aʻe, hiki ke hoʻololi i ka hōʻike gene. Hiki iā ia ke pale i ka histone acetyltransferases (HATs), e alakaʻi ana i ka deacetylation o nā histones a hiki ke hoʻololi i ka transcription o nā genes i komo i ka autophagy a me nā kaʻina hana kelepona ʻē aʻe.

Nā hopena epigenetic:Hiki i ka Spermidine ke hoʻoikaika i ka epigenome ma ka hoʻololi ʻana i ka acetylation o nā histones, ʻo ia nā protein a puni ka DNA i ʻeha. Hiki i kēia ke hoʻopilikia i ka hōʻike ʻana o nā genes a, no laila, ka hana kelepona a me ke olakino.

Hana Mitochondrial:Ua hoʻopili ʻia ʻo Spermidine i ka hana mitochondrial i hoʻomaikaʻi ʻia, he mea koʻikoʻi ia no ka hana ʻana o ka ikehu i loko o nā cell. Hiki iā ia ke hoʻoulu i ka hana ʻana o ka mitochondria hou a hoʻonui i ka hoʻomaʻemaʻe ʻana o nā mea i hōʻino ʻia ma o ke kaʻina i kapa ʻia ʻo mitophagy, ʻo ia ke ʻano o ka autophagy e kuhikuhi pono ana i ka mitochondria.

Nā hopena anti-inflammatory:Ua hōʻike ʻo Spermidine i nā waiwai anti-inflammatory, hiki ke kōkua i ka hōʻemi ʻana i ka mumū e pili ana i ka ʻelemakule a me nā maʻi like ʻole.

Palekana i ke koʻikoʻi oxidative:Ma keʻano he polyamine, hiki i ka spermidine ke hana ma keʻano he antioxidant, e pale ana i nā pūnaewele mai ka pōʻino i hanaʻia e nāʻano oxygen reactive (ROS), i pili i kaʻelemakule a me nā maʻi e pili ana i nā makahiki.

Ka hopena i ka Nutrient Sensing a me Cellular Senescence:Hiki i ka Spermidine ke hana i nā ala ʻike meaʻai, hiki ke hoʻololi i nā kaʻina cellular e like me ka ulu, hoʻonui, a me ka metabolism. Ua manaʻo ʻia e hiki ke hoʻopau i ka senescence cellular, kahi mokuʻāina o ka hopu ʻia ʻana o ka pōʻai cell hiki ʻole ke hoʻihoʻi ʻia e pili ana i ka ʻelemakule a me nā maʻi pili makahiki.

Manaʻo ʻia o ka Wheat Germ Extract Spermidine

Manaʻo ka poʻe akamai i ka hoʻokomo ʻana i ka spermidine i loko o ka meaʻai i kēlā me kēia lā i nā helu liʻiliʻi. ʻOkoʻa ka manaʻo i manaʻo ʻia no nā pōmaikaʻi maikaʻi loa, akā nui nā haʻawina e ʻōlelo nei ma waena o 1 a 5 milligrams i kēlā me kēia lā. Pono e ʻai ʻia me ka makaʻala, ʻoi aku ka nui o nā dosages, ʻoi aku hoʻi ma ke ʻano hoʻohui, a pono e kūkākūkā me kahi ʻoihana mālama ola ma mua o ka hoʻomaka ʻana i kahi ʻano hoʻohui hou.

Ka Manaʻo Manaʻo: ʻO ka wā e hiki mai ana me ka Wheat Germ Extract Spermidine

Hāʻawi ka Wheat germ extract spermidine i kahi manawa hoihoi no ka poʻe e ʻimi nei e hoʻomaikaʻi i ko lākou olakino holoʻokoʻa a lōʻihi. ʻO kona hiki ke hoʻoikaika i ka hoʻoulu hou ʻana o ka cellular, hoʻonui i ka hana cognitive, a kākoʻo i kahi kaʻina hana ʻelemakule olakino e hoʻonoho iā ia ma ke ʻano he kumu hoʻohiki. Me ka hoʻomau ʻana i ka noiʻi, hiki koke i ka spermidine ke lilo i pōhaku kihi o ke olakino pale.