I. Hoolauna
ʻO Phospholipids kahi papa o nā lipid he mau mea koʻikoʻi o nā membrane cell a loaʻa kahi ʻano kūʻokoʻa me kahi poʻo hydrophilic a me nā huelo hydrophobic.ʻO ke ʻano amphipathic o nā phospholipids hiki iā lākou ke hana i nā bilayers lipid, ʻo ia ke kumu o nā membrane cell.Hoʻokumu ʻia nā Phospholipids me kahi iwi kuamoʻo glycerol, ʻelua kaulahao momona momona, a me kahi pūʻulu phosphate, me nā hui ʻaoʻao like ʻole i pili i ka phosphate.Hāʻawi kēia ʻano i nā phospholipids i ka hiki ke hoʻohui iā ia iho i loko o nā lipid bilayers a me nā vesicles, he mea koʻikoʻi no ka pono a me ka hana o nā membrane biological.
He koʻikoʻi ko Phospholipids i nā ʻoihana like ʻole ma muli o ko lākou mau waiwai kūʻokoʻa, me ka emulsification, solubilization, a me nā hopena hoʻopaʻa.I ka ʻoihana meaʻai, hoʻohana ʻia nā phospholipids e like me nā emulsifiers a me nā stabilizers i nā meaʻai i hoʻoponopono ʻia, a me nā mea nutraceutical ma muli o ko lākou mau pono olakino.I nā mea hoʻonaninani, hoʻohana ʻia nā phospholipids no kā lākou emulsifying a moisturizing waiwai, a no ka hoʻomaikaʻi ʻana i ka hāʻawi ʻana i nā mea ikaika i ka ʻili a me nā huahana mālama pilikino.Hoʻohui ʻia, loaʻa i nā phospholipids nā noi nui i nā lāʻau lapaʻau, ʻoi loa i nā ʻōnaehana lawe lāʻau a me ka hoʻokumu ʻana, ma muli o ko lākou hiki ke hoʻopili a hāʻawi i nā lāʻau lapaʻau i nā pahuhopu kikoʻī i ke kino.
II.Ke kuleana o Phospholipids i ka meaʻai
A. Emulsification a stabilizing waiwai
Hoʻohana nā Phospholipids ma ke ʻano he emulsifier koʻikoʻi i ka ʻoihana meaʻai ma muli o ko lākou ʻano amphiphilic.ʻAe kēia iā lākou e launa pū me ka wai a me ka ʻaila, e hana maikaʻi iā lākou i ka hoʻopaʻa ʻana i nā emulsions, e like me ka mayonnaise, nā pāpale salakeke, a me nā huahana waiu like ʻole.Hoʻopili ʻia ke poʻo hydrophilic o ka molekole phospholipid i ka wai, ʻoiai ua hoʻihoʻi ʻia nā huelo hydrophobic e ia, e hopena i ka hoʻokumu ʻana i kahi pilina paʻa ma waena o ka aila a me ka wai.Kōkua kēia waiwai i ka pale ʻana i ka hoʻokaʻawale ʻana a mālama i ka hāʻawi like ʻana o nā mea ʻai i nā huahana meaʻai.
B. Hoʻohana i ka hana ʻai a me ka hana ʻana
Hoʻohana ʻia nā Phospholipids i ka hoʻoili ʻana i nā meaʻai no kā lākou mau waiwai hana, me ko lākou hiki ke hoʻololi i nā ʻano, hoʻomaikaʻi i ka viscosity, a hāʻawi i ke kūpaʻa i nā huahana meaʻai.Hoʻohana pinepine ʻia lākou i ka hana ʻana i nā meaʻai i kālua ʻia, nā mea ʻono, a me nā huahana waiu e hoʻonui ai i ka maikaʻi a me ke ola o nā huahana hope loa.Hoʻohui ʻia, hoʻohana ʻia nā phospholipids ma ke ʻano he anti-sticking agents i ka hana ʻana i ka ʻiʻo, ka moa, a me nā huahana iʻa.
C. Nā pono olakino a me nā pono meaʻai
Hāʻawi ka Phospholipids i ka maikaʻi o nā meaʻai ma ke ʻano he mea kūlohelohe o nā kumu meaʻai he nui, e like me nā hua manu, soybeans, a me nā huahana waiu.Hoʻomaopopo ʻia lākou no kā lākou pono olakino olakino, me kā lākou kuleana i ka hoʻolālā cellular a me ka hana, a me ko lākou hiki ke kākoʻo i ke olakino lolo a me ka hana cognitive.Ua noiʻi ʻia nā Phospholipids no ko lākou hiki ke hoʻomaikaʻi i ka metabolism lipid a me ke olakino cardiovascular.
III.Nā noi o Phospholipids i nā mea hoʻonani
A. Emulsifying a moisturizing hopena
Hoʻohana nui ʻia nā Phospholipids i nā mea hoʻonaninani a me nā huahana mālama pilikino no kā lākou hopena emulsifying a moisturizing.Ma muli o ko lākou ʻano amphiphilic, hiki i nā phospholipids ke hana i nā emulsion paʻa, e ʻae ana i ka wai a me nā mea ʻaila i hui pū ʻia, ka hopena i nā creams a me nā lotions me nā ʻano ʻano like ʻole.Eia kekahi, ʻo ke ʻano kūʻokoʻa o ka phospholipids e hiki ai iā lākou ke hoʻohālikelike i ka pale lipid maoli o ka ʻili, e hoʻomaʻemaʻe pono i ka ʻili a pale i ka nalowale o ka wai, he mea pono ia no ka mālama ʻana i ka hydration o ka ʻili a pale i ka maloʻo.
Ua hoʻohana ʻia nā Phospholipids e like me ka lecithin ma ke ʻano he emulsifiers a me ka moisturizers i nā ʻano mea hoʻonaninani a me nā huahana mālama ʻili, e komo pū me nā ʻaila, nā lotions, nā serum, a me nā pale lā.ʻO kā lākou hiki ke hoʻomaikaʻi i ke ʻano, ka manaʻo, a me ka moisturizing waiwai o kēia mau huahana e lilo lākou i mea waiwai i ka ʻoihana hoʻonaninani.
B. Hoʻonui i ka hāʻawi ʻana i nā mea hana
He kuleana koʻikoʻi ka Phospholipids i ka hoʻomaikaʻi ʻana i ka hāʻawi ʻana i nā mea hana i loko o nā mea hoʻonaninani a me nā ʻili.ʻO ko lākou hiki ke hana i nā liposomes, nā vesicles i haku ʻia me nā bilayers phospholipid, e ʻae i ka encapsulation a me ka pale ʻana i nā pūhui hana, e like me nā huaora, antioxidants, a me nā mea pono ʻē aʻe.Kōkua kēia encapsulation i ka hoʻomaikaʻi ʻana i ka paʻa, bioavailability, a me ka hāʻawi ʻia ʻana o kēia mau mea hoʻoikaika i ka ʻili, e hoʻonui ana i ko lākou pono i nā mea hoʻonaninani a me nā huahana mālama ʻili.
Eia kekahi, ua hoʻohana ʻia nā ʻōnaehana hāʻawi phospholipid e lanakila ai i nā pilikia o ka hāʻawi ʻana i nā pūhui hydrophobic a me ka hydrophilic ikaika, e hoʻolilo iā lākou i nā mea lawe maʻamau no ka nui o nā mea hoʻonaninani.Ua hoʻohana nui ʻia nā ʻano liposomal i loaʻa nā phospholipids i nā huahana anti-old, moisturizing, a me ka hoʻoponopono ʻana i ka ʻili, kahi e hiki ai iā lākou ke hāʻawi pono i nā mea hana i nā ʻili ʻili.
C. Ke kuleana i ka mālama ʻili a me nā huahana mālama pilikino
He kuleana koʻikoʻi ka Phospholipids i ka mālama ʻili a me nā huahana mālama pilikino, e hāʻawi ana i kā lākou hana a me ka pono.Ma waho aʻe o kā lākou emulsifying, moisturizing, a me ka hoʻonui ʻana i ka hāʻawi ʻana, hāʻawi pū kekahi phospholipids i nā pono e like me ka hoʻomaʻamaʻa ʻili, pale, a me ka hoʻoponopono.Hiki i kēia mau molekala maʻalahi ke kōkua i ka hoʻomaikaʻi ʻana i ka ʻike sensory holoʻokoʻa a me ka hana ʻana o nā huahana cosmetic, e hoʻolilo iā lākou i mea kaulana i loko o nā ʻano hana mālama ʻili.
ʻO ka hoʻokomo ʻana o nā phospholipids i ka mālama ʻili a me nā huahana mālama pilikino e hoʻonui ʻia ma mua o nā moisturizers a me nā creams, no ka mea, hoʻohana ʻia lākou i nā mea hoʻomaʻemaʻe, nā sunscreens, nā mea hoʻomaʻemaʻe, a me nā huahana mālama lauoho.ʻO kā lākou ʻano multifunctional hiki iā lākou ke hoʻoponopono i nā pono mālama ʻili a me ka lauoho, e hāʻawi ana i nā pono cosmetic a me ka therapeutic i nā mea kūʻai.
IV.Ka hoʻohana ʻana i nā Phospholipids i nā lāʻau lapaʻau
A. Hāʻawi ʻia a me ka hana ʻana i ka lāʻau
He kuleana koʻikoʻi ka Phospholipids i ka hāʻawi ʻana i ka lāʻau lapaʻau a me ka hoʻokumu ʻana ma muli o ko lākou ʻano amphiphilic, e hiki ai iā lākou ke hana i nā lipid bilayers a me nā vesicles hiki ke hoʻopili i nā lāʻau hydrophobic a hydrophilic.Hāʻawi kēia waiwai i nā phospholipids e hoʻomaikaʻi i ka solubility, kūpaʻa, a me ka bioavailability o nā lāʻau hoʻoheheʻe maikaʻi ʻole, e hoʻonui ana i ko lākou hiki no ka hoʻohana therapeutic.Hiki i nā ʻōnaehana hāʻawi lāʻau lapaʻau Phospholipid ke pale aku i nā lāʻau mai ka hoʻohaʻahaʻa ʻana, ka hoʻokuʻu ʻana i nā kinetics, a me ka hoʻopaʻa ʻana i nā cell a i ʻole nā kiko kikoʻī, e hāʻawi ana i ka hoʻomaikaʻi ʻana i ka lāʻau lapaʻau a me nā hopena ʻaoʻao.
Ua hoʻohana ʻia ka hiki o nā phospholipids e hana i nā hale i hui pū ʻia, e like me nā liposomes a me nā micelles, i ka hoʻomohala ʻana i nā ʻano lāʻau lapaʻau like ʻole, me ka waha, parenteral, a me nā ʻano hoʻohālikelike topical.Hoʻopili pinepine ʻia nā phospholipids e lanakila ai i nā pilikia e pili ana i ka solubility a me ka absorption o ka lāʻau, a me ka hoʻomaikaʻi ʻana i nā hopena therapeutic o nā huahana lāʻau.
B. Liposomal nā ʻōnaehana lawe lāʻau
ʻO nā ʻōnaehana hāʻawi lāʻau liposomal kahi hiʻohiʻona koʻikoʻi o ka hoʻohana ʻana o ka phospholipids i nā noi lāʻau.ʻO nā liposomes, i haku ʻia me nā phospholipid bilayers, hiki ke hoʻopili i nā lāʻau lapaʻau i loko o kā lākou aqueous core a i ʻole lipid bilayers, e hāʻawi ana i kahi wahi palekana a me ka hoʻomalu ʻana i ka hoʻokuʻu ʻana o nā lāʻau.Hiki ke hoʻopili ʻia kēia mau ʻōnaehana lawe lāʻau i mea e hoʻomaikaʻi ai i ka lawe ʻana i nā ʻano lāʻau lapaʻau like ʻole, me ka chemotherapeutic agents, antibiotics, a me nā lāʻau lapaʻau, e hāʻawi ana i nā pono e like me ka lōʻihi o ka holo ʻana, hoʻemi ʻia ka ʻona, a me ka hoʻonui ʻia ʻana o nā kiko a i ʻole nā cell.
Hiki i ka versatility o liposomes ke hoʻololi i ko lākou nui, ka uku, a me nā waiwai o ka ʻili e hoʻopaʻa i ka hoʻouka ʻana i ka lāʻau lapaʻau, kūpaʻa, a me ka hāʻawi ʻana i nā kiko.ʻO kēia maʻalahi i alakaʻi i ka hoʻomohala ʻana i nā formulations liposomal i ʻae ʻia no nā noi therapeutic like ʻole, e hōʻike ana i ke koʻikoʻi o nā phospholipids i ka holomua ʻana i nā ʻenehana lawe lāʻau.
C. Nā noi kūpono i ka noiʻi olakino a me ka mālama ʻana
Paʻa ka Phospholipids i nā noi i ka noiʻi olakino a me ka mālama ʻana ma mua o nā ʻōnaehana lawe lāʻau maʻamau.ʻO kā lākou hiki ke launa pū me nā membrane cell a me ka hoʻololi ʻana i nā kaʻina cellular e hāʻawi i nā manawa kūpono no ka hoʻomohala ʻana i nā hoʻolālā therapeutic novel.Ua noiʻi ʻia nā hoʻokumu ʻana o Phospholipid no ko lākou hiki ke kuhikuhi i nā ala intracellular, modulate gene expression, a hoʻonui i ka pono o nā mea lapaʻau like ʻole, e hōʻike ana i nā noi ākea ma nā wahi e like me ka gene therapy, regenerative medicine, a me ka mālama ʻana i ka maʻi kanesa.
Eia kekahi, ua ʻimi ʻia nā phospholipids no kā lākou kuleana i ka hoʻolaha ʻana i ka hoʻoponopono hou ʻana a me ka hoʻoponopono hou ʻana, e hōʻike ana i ka hiki ke hoʻōla i ka ʻeha, ʻenehana ʻenehana, a me ka lāʻau lapaʻau hou.ʻO ko lākou hiki ke hoʻohālikelike i nā membrane cell kūlohelohe a me ka launa pū ʻana me nā ʻōnaehana olaola e hana i ka phospholipids i ala hoʻohiki no ka holomua ʻana i ka noiʻi olakino a me nā ʻano hana lapaʻau.
V. Nā Paʻi a me nā kuhikuhi e hiki mai ana
A. Nā manaʻo hoʻoponopono a me nā pilikia palekana
ʻO ka hoʻohana ʻana i nā phospholipids i ka meaʻai, nā mea hoʻonaninani, a me nā lāʻau lapaʻau e hāʻawi i nā manaʻo like ʻole a me nā hopohopo palekana.I ka ʻoihana meaʻai, hoʻohana pinepine ʻia nā phospholipids e like me nā emulsifiers, stabilizers, a me nā ʻōnaehana lawe no nā mea hana.ʻO nā kino hoʻoponopono, e like me ka Food and Drug Administration (FDA) ma ʻAmelika Hui Pū ʻIa a me ka European Food Safety Authority (EFSA) ma ʻEulopa, e nānā i ka palekana a me ka hōʻailona ʻana i nā huahana meaʻai i loaʻa nā phospholipids.Pono nā loiloi palekana e hōʻoia i ka palekana o nā meaʻai e pili ana i ka phospholipid no ka ʻai ʻana a me ka mālama ʻana i nā lula i hoʻopaʻa ʻia.
I ka ʻoihana hoʻonaninani, hoʻohana ʻia nā phospholipids i ka mālama ʻili, mālama lauoho, a me nā huahana mālama pilikino no kā lākou emollient, moisturizing, a me ka hoʻonui ʻana i ka ʻili.ʻO nā ʻoihana hoʻoponopono, e like me ka European Union's Cosmetics Regulation a me ka US Food and Drug Administration (FDA), e nānā i ka palekana a me ka hōʻailona ʻana i nā huahana cosmetic i loaʻa nā phospholipids e hōʻoia i ka pale o ka mea kūʻai.Hana ʻia nā loiloi palekana a me nā haʻawina toxicological e loiloi i ka ʻike palekana o nā mea hoʻonaninani phospholipid-based.
I ka ʻāpana lāʻau lapaʻau, ʻo ka palekana a me ka noʻonoʻo hoʻoponopono o ka phospholipids e hoʻopili i kā lākou hoʻohana ʻana i nā ʻōnaehana lawe lāʻau, liposomal formulations, a me nā mea hoʻohui lāʻau.ʻO nā mana hoʻoponopono, e like me ka FDA a me ka European Medicines Agency (EMA), e loiloi i ka palekana, ka pono, a me ka maikaʻi o nā huahana lāʻau lapaʻau i loaʻa nā phospholipids ma o nā kaʻina loiloi preclinical a me nā kaʻina loiloi.ʻO nā pilikia palekana e pili ana i nā phospholipids i loko o nā lāʻau lapaʻau e pili ana i nā mea ʻawaʻawa, immunogenicity, a me ka launa pū me nā mea lāʻau.
B. Nā ʻano hou a me nā mea hou
ʻO ka hoʻohana ʻana i nā phospholipids i ka meaʻai, nā mea hoʻonaninani, a me nā lāʻau lapaʻau ke ʻike nei i nā ʻano hou a me nā hoʻomohala hou.I ka ʻoihana meaʻai, ʻo ka hoʻohana ʻana i nā phospholipids e like me nā emulsifiers kūlohelohe a me nā stabilizers e loaʻa ana i ka traction, i alakaʻi ʻia e ka ulu nui ʻana no ka lepili maʻemaʻe a me nā meaʻai kūlohelohe.ʻO nā ʻenehana hou, e like me nā nanoemulsions i hoʻopaʻa ʻia e nā phospholipids, ke ʻimi ʻia nei e hoʻonui i ka solubility a me ka bioavailability o nā mea meaʻai hana, e like me nā pūhui bioactive a me nā huaora.
I loko o ka ʻoihana hoʻonaninani, ʻo ka hoʻohana ʻana i nā phospholipids i nā hoʻolālā mālama ʻili kiʻekiʻe he ʻano koʻikoʻi, me ka nānā ʻana i nā ʻōnaehana hāʻawi lipid-based no nā mea hana a me ka hoʻoponopono ʻana i ka ʻili.ʻO nā formulations e hoʻokomo ana i nā nanocarriers phospholipid, e like me nā liposomes a me nā nanostructured lipid carriers (NLCs), ke holomua nei i ka pono a me ka hāʻawi ʻia ʻana o nā mea hoʻonaninani, e hāʻawi ana i nā mea hou i ka anti-aging, ka pale o ka lā, a me nā huahana mālama ʻili pilikino.
I loko o ka ʻāpana lāʻau lapaʻau, ʻo nā ʻano e kū mai ana i ka hāʻawi ʻana i ka lāʻau lapaʻau phospholipid i hoʻopili ʻia i ka lāʻau lapaʻau pilikino, nā lāʻau lapaʻau i manaʻo ʻia, a me nā ʻōnaehana lawe lāʻau hui pū.Ke kūkulu ʻia nei nā mea lawe lipid-based, me nā nanoparticles lipid-polymer hybrid a me nā conjugates lāʻau lapaʻau lipid-based, e hoʻonui i ka lawe ʻana i ka moʻolelo a me nā lāʻau lapaʻau e kū nei, e hoʻoponopono ana i nā pilikia e pili ana i ka solubility o ka lāʻau, kūpaʻa, a me ka huli ʻana i ka pūnaewele.
C. Hiki i ka hana like ʻana o nā ʻoihana a me nā manawa hoʻomohala
Hāʻawi ka versatility o phospholipids i nā manawa kūpono no ka hui ʻana o ka ʻoihana cross-industry a me ka hoʻomohala ʻana i nā huahana hou ma ke kikowaena o nā meaʻai, nā mea hoʻonaninani, a me nā lāʻau lapaʻau.Hiki i nā hui cross-industry ke hoʻololi i ka ʻike, ʻenehana, a me nā hana maikaʻi loa e pili ana i ka hoʻohana ʻana i nā phospholipids ma nā ʻāpana like ʻole.No ka laʻana, hiki ke hoʻohana ʻia ka loea i nā ʻōnaehana hāʻawi lipid-based mai ka ʻoihana lāʻau lapaʻau e hoʻomaikaʻi i ka hoʻolālā a me ka hana o nā mea hana lipid-based i ka meaʻai a me nā mea hoʻonaninani.
Eia kekahi, ʻo ka hui ʻana o ka meaʻai, nā mea hoʻonaninani, a me nā lāʻau lapaʻau ke alakaʻi nei i ka hoʻomohala ʻana i nā huahana multifunctional e pili ana i ke olakino, olakino, a me nā pono nani.No ka laʻana, ke kū mai nei nā nutraceuticals a me nā cosmeceuticals e hoʻokomo ana i nā phospholipids ma muli o ka hui like ʻana o nā ʻoihana cross-industry, e hāʻawi ana i nā hopena hou e hāpai ana i nā pono olakino o loko a me waho.Hoʻoulu pū kēia mau hui i nā manawa no ka noiʻi a me ka hoʻomohala ʻana i ka ʻimi ʻana i nā synergies a me nā noi hou o ka phospholipids i nā ʻano huahana multifunctional.
VI.Ka hopena
A. Recap o ka versatility a me ke koʻikoʻi o phospholipids
He koʻikoʻi ko Phospholipids i nā ʻoihana like ʻole, e hāʻawi ana i kahi ākea o nā noi i ka meaʻai, nā mea hoʻonaninani, a me nā ʻāpana lāʻau.ʻO kā lākou ʻano kemika kūʻokoʻa, e komo pū ana me nā ʻāpana hydrophilic a me ka hydrophobic, hiki iā lākou ke hana ma ke ʻano he emulsifiers, stabilizers, a me nā ʻōnaehana lawe no nā mea hana.I ka ʻoihana meaʻai, hāʻawi nā phospholipids i ka paʻa a me ke ʻano o nā meaʻai i hoʻoponopono ʻia, ʻoiai i nā mea hoʻonaninani, hāʻawi lākou i ka moisturizing, emollient, a me nā mea e hoʻonui ai i ka pale i nā huahana skincare.Eia kekahi, hoʻohana ka ʻoihana lāʻau lapaʻau i nā phospholipids i nā ʻōnaehana lawe lāʻau, liposomal formulations, a ma ke ʻano he lāʻau lapaʻau ma muli o ko lākou hiki ke hoʻonui i ka bioavailability a kuhikuhi i nā wahi kikoʻī o ka hana.
B. Nā hopena no ka noiʻi e hiki mai ana a me nā noi ʻoihana
Ke hoʻomau nei ka noiʻi ʻana i ka phospholipids, aia kekahi mau manaʻo no nā noiʻi e hiki mai ana a me nā noi ʻoihana.ʻO ka mea mua, ʻo ka noiʻi hou ʻana i ka palekana, efficacy, a me nā synergies i waena o phospholipids a me nā mea hoʻohui ʻē aʻe e hiki ke hoʻomākaukau i ke ala no ka hoʻomohala ʻana i nā huahana multifunctional hou e hoʻokō i nā pono e ulu nei o nā mea kūʻai.Eia kekahi, ʻo ka ʻimi ʻana i ka hoʻohana ʻana i nā phospholipids i nā ʻenehana hou e like me nā nanoemulsions, nā nanocarriers lipid-based, a me nā nanoparticles lipid-polymer hybrid e paʻa i ka ʻōlelo hoʻohiki no ka hoʻonui ʻana i ka bioavailability a me ka hāʻawi ʻana i nā pūhui bioactive i ka meaʻai, nā mea hoʻonaninani, a me nā lāʻau lapaʻau.Hiki i kēia noiʻi ke alakaʻi i ka hoʻokumu ʻana i nā ʻano huahana hou e hāʻawi i ka hana maikaʻi a me ka pono.
Mai kahi hiʻohiʻona ʻoihana, ʻo ke koʻikoʻi o nā phospholipids i nā noi like ʻole e hōʻike ana i ke koʻikoʻi o ka hoʻomau mau ʻana a me ka hui pū ʻana i loko a ma waena o nā ʻoihana.Me ka ulu nui o ka noi no nā mea kūlohelohe a me ka hana, ʻo ka hoʻohui ʻana o nā phospholipids i ka meaʻai, nā mea hoʻonaninani, a me nā lāʻau lapaʻau e hāʻawi i kahi manawa kūpono no nā ʻoihana e hoʻomohala i nā huahana kiʻekiʻe, hoʻomau e kūlike me nā makemake o nā mea kūʻai.Eia kekahi, hiki ke hoʻololi ʻia nā noi ʻoihana ʻoihana o ka phospholipids i nā hui cross-sector, kahi e hoʻololi ʻia ai ka ʻike a me nā ʻenehana mai ka meaʻai, nā mea hoʻonaninani, a me nā ʻoihana lāʻau lapaʻau e hana i nā huahana hou, multifunctional e hāʻawi ana i nā pono olakino a me ka nani.
I ka hopena, ʻo ka versatility o phospholipids a me ko lākou koʻikoʻi i ka meaʻai, nā mea hoʻonaninani, a me nā lāʻau lapaʻau e hoʻolilo iā lākou i mea hoʻohui o nā huahana he nui.ʻO kā lākou hiki ke noiʻi a me nā noi ʻoihana e hiki mai ana ke ala no ka holomua mau ʻana i nā mea hana multifunctional a me nā ʻano hana hou, e hana ana i ka ʻāina o ka mākeke honua ma nā ʻoihana like ʻole.
Kuhikuhi:
1. Mozafari, MR, Johnson, C., Hatziantoniou, S., & Demetzos, C. (2008).Nā Nanoliposome a me kā lākou mau noi i ka nanotechnology meaʻai.Nūpepa o Liposome Research, 18 (4), 309-327.
2. Mezei, M., & Gulasekharam, V. (1980).Liposomes - He ʻōnaehana hāʻawi lāʻau koho no ke ala o ka hoʻokele.ʻO ke ʻano o ka lotion.ʻIke Ola, 26(18), 1473-1477.
3. Williams, AC, & Barry, BW (2004).Nā mea hoʻonui komo.Nā Manaʻo Hoʻolaha Lapaʻau Kiʻekiʻe, 56 (4), 603-618.
4. Arouri, A., & Mouritsen, OG (2013).Phospholipids: hanana, biochemistry a me ka nānā ʻana.Handbook of hydrocolloids (Second Edition), 94-123.
5. ʻO Berton-Carabin, CC, Ropers, MH, Genot, C., & Lipid Emulsions a me kā lākou hoʻolālā - Journal of Lipid Research.(2014).emulsifying waiwai o ka meaʻai-grade phospholipids.Nūpepa o ka Lipid Research, 55 (6), 1197-1211.
6. Wang, C., Zhou, J., Wang, S., Li, Y., Li, J., & Deng, Y. (2020).Nā pōmaikaʻi olakino a me nā noi o nā phospholipids kūlohelohe i ka meaʻai: He Review.ʻEpekema Meaʻai Hou a me nā ʻenehana hou, 102306. 8. Blezinger, P., & Harper, L. (2005).Phospholipids i ka meaʻai hana.In Dietary Modulation of Cell Signaling Pathways (pp. 161-175).CRC Press.
7. Frankenfeld, BJ, & Weiss, J. (2012).Phospholipids i ka meaʻai.In Phospholipids: Characterization, Metabolism, and Novel Biological Applications (pp. 159-173).AOCS Press.7. Hughes, AB, & Baxter, NJ (1999).Emulsifying waiwai o phospholipids.In Food emulsions and foams (pp. 115-132).ʻAhahui Aliʻi o ke Kemika
8. Lopes, LB, & Bentley, MVLB (2011).ʻO Phospholipids i nā ʻōnaehana lawe hoʻonaninani: e ʻimi ana i ka mea maikaʻi loa mai ke ʻano.I nā Nanocosmetics a me nā nanomedicines.Springer, Berlin, Heidelberg.
9. Schmid, D. (2014).ʻO ke kuleana o nā phospholipids kūlohelohe i nā hoʻolālā hoʻonaninani a me ka mālama pilikino.In Advances in Cosmetics Science (pp. 245-256).Springer, Cham.
10. Jenning, V., & Gohla, SH (2000).Hoʻopili ʻia o nā retinoids i loko o nā nanoparticles lipid paʻa (SLN).Nūpepa o Microencapsulation, 17 (5), 577-588.5. Rukavina, Z., Chiari, A., & Schubert, R. (2011).Hoʻomaikaʻi ʻia nā ʻano hoʻonaninani ma o ka hoʻohana ʻana i nā liposomes.I nā Nanocosmetics a me nā nanomedicines.Springer, Berlin, Heidelberg.
11. Neubert, RHH, Schneider, M., & Kutkowska, J. (2005).Phospholipids i loko o nā mea hoʻomaʻemaʻe a me nā lāʻau lapaʻau.In Anti-Aging in Ophthalmology (pp. 55-69).Springer, Berlin, Heidelberg.6. Bottari, S., Freitas, RCD, Villa, RD, & Senger, AEVG (2015).Ka hoʻohana ʻana i nā phospholipids: kahi hoʻolālā hoʻohiki e hoʻoponopono i ka pale ʻili.Hoʻolālā Lapaʻau o kēia manawa, 21(29), 4331-4338.
12. Torchilin, V. (2005).Handbook of pharmacokinetics pono, pharmacodynamics a me ka lāʻau metabolism no nā ʻepekema ʻenehana.Springer Science & Pāʻoihana Media.
13. Lā, AA, & Nagarsenker, M. (2008).Hoʻolālā a me ka loiloi ʻana o nā ʻōnaehana lawe lāʻau emulsifying ponoʻī (SEDDS) o nimodipine.AAPS PharmSciTech, 9(1), 191-196.
2. Allen, TM, & Cullis, PR (2013).Nā ʻōnaehana hāʻawi lāʻau liposomal: Mai ka manaʻo i nā noi lapaʻau.Nā Manaʻo Hoʻolaha Lapaʻau Kiʻekiʻe, 65 (1), 36-48.5. Bozzuto, G., & Molinari, A. (2015).ʻO nā liposome e like me nā mea nanomedical.Nupepa International o Nanomedicine, 10, 975.
Lichtenberg, D., & Barenholz, Y. (1989).ʻO ka pono hoʻouka ʻana o nā lāʻau liposome: kahi hana hana a me kāna hōʻoia hoʻokolohua.Laau Laau Laau, 303-309.6. Simons, K., & Vaz, WLC (2004).Nā ʻōnaehana hoʻohālike, nā lāʻau lipid, a me nā membrane cell.Nānā Makahiki o Biophysics a me Biomolecular Structure, 33 (1), 269-295.
Williams, AC, & Barry, BW (2012).Nā mea hoʻonui komo.In Dermatological Formulations: Percutaneous Absorption (pp. 283-314).CRC Press.
Muller, RH, Radtke, M., & Wissing, SA (2002).Solid lipid nanoparticles (SLN) a me nanostructured lipid carriers (NLC) i loko o ka cosmetic a me ka dermatological hoomakaukau.Nā Manaʻo Hoʻolaha Lapaʻau Kiʻekiʻe, 54, S131-S155.
2. Severino, P., Andreani, T., Macedo, AS, Fangueiro, JF, Santana, MHA, & Silva, AM (2018).ʻO ke kūlana kiʻekiʻe o kēia manawa a me nā ʻano hou o nā lipid nanoparticles (SLN a me NLC) no ka lawe ʻana i ka lāʻau lapaʻau waha.Nūpepa o ka lāʻau lapaʻau ʻepekema a me ʻenehana, 44, 353-368.5. Torchilin, V. (2005).Handbook of essential pharmacokinetics, pharmacodynamics and drug metabolism no nā ʻepekema ʻenehana.Springer Science & Pāʻoihana Media.
3. Williams, KJ, & Kelley, RL (2018).Biotechnology lāʻau lapaʻau ʻoihana.John Wiley & Keikikane.6. Simons, K., & Vaz, WLC (2004).Nā ʻōnaehana hoʻohālike, nā lāʻau lipid, a me nā membrane cell.Nānā Makahiki o Biophysics a me Biomolecular Structure, 33 (1), 269-295.
Ka manawa hoʻouna: Dec-27-2023
