He Antioxidant Kūlohelohe—ʻO ka Ginkgo Leaf Extract!

1. Hopena ma ka ʻōnaehana cardiovascular
(1) Hiki i ka ʻāpana lau Ginkgo ke kāohi i ka hana o ka angiotensin-converting enzyme (ACE) i loko o ke koko kanaka maʻamau, a laila e kāohi ana i ka ʻūlū ʻana o nā arterioles, ka hoʻonui ʻana i nā kīʻaha koko, a me ka hoʻonui ʻana i ke kahe koko.
(2) Hiki i ka ʻāpana lau Ginkgo ke pale i ka emi ʻana o ka myocardial i loko o nā ʻiole kāne i hoʻokumu ʻia e ka hoʻokomo ʻana o ka bupivacaine i loko o ke kino, kāohi i ka ʻūlū ʻana o ke aʻa coronary i loko o ke kanaka a me nā puaʻa i hoʻokumu ʻia e ka hypoxia, a hoʻopau i ka PAF (platelet-activating factor) e hoʻoulu ai i ka arrhythmia i nā ʻīlio. Hiki iā ia ke kāohi i ka hana ʻino o ka puʻuwai i hoʻokumu ʻia e nā maʻi ʻaleka puʻuwai i nā puaʻa guinea i hoʻokaʻawale ʻia.
(3) Hiki i ka ʻāpana lau Ginkgo ke hoʻonui nui i nā kīʻaha koko lolo o nā pōpoki a me nā ʻīlio i hoʻopaʻa ʻia, hoʻonui i ke kahe koko lolo, a hōʻemi i ke kūʻē ʻana o nā kīʻaha koko lolo. Hiki i ka ʻāpana lau Ginkgo ke pale aku i ka hoʻonui ʻia ʻana o ke anawaena microvascular mesenteric i hoʻokumu ʻia e ka endotoxin intravenous. I ke kumu hoʻohālike endotoxin canine, pale ka ʻāpana Ginkgo biloba i nā loli hemodynamic; i ke kumu hoʻohālike māmā hipa, pale ka ʻāpana Ginkgo biloba i ke koko kiʻekiʻe a me ka edema pulmonary i hoʻokumu ʻia e ka maʻi kahe lymphatic i hoʻokumu ʻia e ka endotoxin.
(4) Ua hoʻokomo ʻia nā ʻiole i loko o ka ʻōpū me 5ml/kg o nā flavonoids lau ginkgo i kēlā me kēia lā. Ma hope o 40 mau lā, ua emi nui ka nui o ka triglyceride serum. Ua hāʻawi ʻia ka Ginkgo biloba extract (20 mg/kg i kēlā me kēia lā) i nā lāpaki e loaʻa ana i ka ʻai maʻamau a hypercholesterolemic. Ma hope o hoʻokahi mahina, ua emi nui nā pae o ka cholesterol hyper-esterified i loko o ka plasma a me ka aorta o nā lāpaki e loaʻa ana i ka ʻai atherogenic. Eia naʻe, ua mau ka loli o nā pae cholesterol manuahi.
(5) ʻO Ginkgo terpene lactone kahi mea pale PAF receptor kikoʻī loa. Hiki i ka Ginkgo leaf extract a i ʻole ginkgo terpene lactone ke kāohi i ka platelet-activating factor (PAF) a me ka cyclooxygenase a i ʻole lipoxygenase. Ua ʻae maikaʻi ʻia ka Ginkgo leaf extract a ua kūʻē i ka platelet aggregation i hoʻokumu ʻia e PAF akā ʻaʻole i hoʻopilikia i ka aggregation i hoʻokumu ʻia e ADP.

2. Hopena ma ka ʻōnaehana nerve waena
(1) Hoʻopilikia ka ʻāpana lau Ginkgo i ka ʻōnaehana endocrine a me ka pilina ma waena o ka ʻōnaehana pale a me ka ʻōnaehana nerve waena ma o ka pale ʻana i ka hana o PAF. Hiki iā ia ke hoʻoulu i ka metabolism kahe o ka lolo a hoʻomaikaʻi i ka hana hoʻomanaʻo.
(2) Loaʻa i nā Ginkgo terpene lactones nā hopena antidepressant, a pili ko lākou hopena antidepressant i ka ʻōnaehana nerve monoaminergic waena.
(3) Ma waho aʻe o ka ʻoiaʻiʻo e hiki i ka ʻāpana lau Ginkgo ke hoʻomaikaʻi nui i ka hemahema hoʻomanaʻo ʻano hemahema i hoʻokumu ʻia e NaNO2, ʻo kona hopena anti-hypoxic e pili ana paha i kona hoʻonui ʻana i ke kahe koko o ka lolo a me ka hoʻomaikaʻi ʻana i ka metabolism ikehu o ka lolo i ka wā hypoxia.
(4) Hoʻomaikaʻi nui ka ʻāpana lau Ginkgo i nā maʻi lolo o nā gerbils i hoʻokumu ʻia e ka ligation a me ka recirculation o nā ʻaʻa carotid ʻelua a pale i ka hōʻino ʻana o ka lolo i nā gerbils i hoʻokumu ʻia e ka ischemia a me ka congestion; hoʻonui i ka hana o nā ʻīlio ma hope o ka ischemia lolo multi-focal Hoʻōla mua ka neuronal a me ka hōʻemi ʻana i ka hōʻino neuronal ma hope o ka ischemia ma ka hippocampus o ka lolo gerbil; hoʻemi nui i ka nalowale o ATP, AMP, creatine a me creatine phosphate i ka lolo ischemic o ka ʻīlio mongrel. He mea pono ka Ginkgo biloba lactone B i ka mālama lapaʻau o ka hahau.

3. Hopena ma ka ʻōnaehana hoʻoheheʻe
(1) Hiki i ka ʻāpana lau Ginkgo ke hoʻomaikaʻi nui i nā ʻōpū gastric a me nā ʻōpū i loko o nā ʻiole i hoʻokumu ʻia e PAF a me endotoxin, a hiki ke pale hapa i ka hōʻino ʻana o ka ʻōpū i hoʻokumu ʻia e ka ethanol.
(2) I loko o nā ʻiole me ka cirrhosis akepaʻa i hoʻokumu ʻia e ka ligation bile duct, ʻo ka hoʻokomo ʻana i loko o ka intravenous o ka ginkgo leaf extract i hoʻemi nui i ke kaomi venous portal hepatic, ka cardiac index, ke kahe koko o nā lālā vein portal, a hoʻomaikaʻi i ka hoʻomanawanui vascular systemic i hoʻohālikelike ʻia me ka placebo. Hōʻike kēia he hopena therapeutic ka ginkgo leaf extract i ka cirrhosis akepaʻa. Hiki iā ia ke ālai i ka hoʻokumu ʻia ʻana o nā radical oxygen-free i ka pancreatitis acute i ka ʻiole i hoʻokumu ʻia e cholecystokinin. Hiki i ka Ginkgo terpene lactone B ke loaʻa kahi kuleana i ka mālama ʻana i ka pancreatitis acute.

4. Hopena ma ka ʻōnaehana hanu
(1) Loaʻa i ka ethanol extract o Ginkgo biloba kahi hopena hoʻomaha pololei i ka ʻiʻo laumania tracheal a hiki ke hōʻoluʻolu i nā hopena spasmodic o ka histamine phosphate a me ka acetylcholine ma ka trachea i hoʻokaʻawale ʻia o nā puaʻa guinea, a pale i nā hoʻouka kaua hānō i hoʻokomo ʻia e ka histamine i nā puaʻa guinea.
(2) ʻO ka hoʻokomo ʻana i ka ʻāpana lau Ginkgo i loko o ke kino hiki ke kāohi i ka bronchoconstriction a me ka hyperresponsiveness o nā ʻiole i hoʻokumu ʻia e PAF a me ovalbumin, a pale i ka bronchoconstriction i hoʻokumu ʻia e nā antigens, akā ʻaʻole ia e hoʻopilikia i ka hyperresponsiveness bronchial i hoʻokumu ʻia e indomethacin.
(3) ʻO ka hanu ʻana i ka ʻāpana lau Ginkgo aerosolized ʻaʻole wale ia e kāohi i ka bronchoconstriction akā e kāohi pū i ka hōʻemi ʻana o nā hunaola koko keʻokeʻo a me nā eosinophils i hoʻokumu ʻia e PAF. He mea nui ka ʻāpana lau Ginkgo i ka pale ʻana a me ka mālama ʻana i ka hyperresponsiveness bronchial.

5. Ka hopena anti-kahiko
ʻO nā Ginkgobiflavonoids, isoginkgobiflavonoids, ginkgo biloba, a me quercetin i loko o nā lau ginkgo e kāohi i ka lipid peroxidation, ʻoiai ʻoi aku ka ikaika o ka hana pale ʻana o ka quercetin. Ua hana ʻia nā hoʻokolohua ma luna o nā ʻiole a ua ʻike ʻia e hiki i nā flavonoids lau ginkgo i unuhi ʻia i ka wai (0.95mg/ml) ke hōʻemi nui i ka lipid peroxidation, a ʻo nā flavonoids lau ginkgo i unuhi ʻia i ka waikawa (1.9mg/ml) hiki ke hoʻonui i ka hana serum copper a me zinc SOD a hōʻemi i ka hopena o ka viscosity koko me ka hōʻemi ʻana i ka hana SGPT.

7. Kūlana i ka hōʻole ʻana i ka hoʻoili ʻana a me nā hopena pale ʻē aʻe
Hiki i ka ʻāpana lau Ginkgo ke hoʻolōʻihi i ke ola o nā grafts ʻili, nā xenografts puʻuwai heterotopic, a me nā xenografts akepaʻa orthotopic. Hiki i ka ʻāpana lau Ginkgo ke kāohi i ka hana o nā cell pepehi kanaka maoli o ke kino e kūʻē i nā cell target KC526, a hiki nō hoʻi ke pale aku i ka hana o nā cell pepehi kanaka maoli i hoʻokumu ʻia e interferon.

8. Ka hopena anti-tumor
ʻO ka ʻāpana maka o nā lau ʻōmaʻomaʻo o Ginkgo biloba, ka ʻāpana momona-hoʻoheheʻe ʻia, hiki ke kāohi i ka maʻi Epstein-Barr. Loaʻa i ka waikawa salicylic Heptadecene a me ka bilo-betin ka hana kāohi ikaika; hiki i nā flavonoids āpau o Ginkgo ke hoʻonui i ke kaumaha thymus o nā ʻiole e lawe ana i ka tumor. a me nā pae hana SOD, e hoʻoneʻe ana i ka hiki ke kūʻē i ka tumor o ke kino; hiki i ka quercetin a me myricetin ke kāohi i ka hanana ʻana o nā carcinogens.