Lawe ʻo Stephania i ka pauka Cepharanthine

Inoa Huahana: Stephania Japonica Extract
Kumu Latina: Stephania cephalantha Hayata(Stephania japonica (Thunb.)Miers)/ Stephania epigaea Lo/ Stephania yunnanensis HSLo.
ʻAno: Keʻokeʻo, ʻO ka pauka keʻokeʻo hina
Mea Hana: Cepharanthine 80% -99% HPLC
Māhele i hoʻohana ʻia: Tuber/Root
Noi: Nā huahana mālama ola
Ka helu hehee: 145-155°
Ka hoʻololi kikoʻī: D20+277°(c=2inchloroform)
Punila hoʻolapalapa: 654.03°C (manaʻo koʻikoʻi)
Māmā:1.1761
Hōʻike hoʻohālikelike:1.5300(manaʻo)
Nā kūlana mālama: underinertgas (nitrogen a i ʻole Argon) ma 2-8 ° C
Solubility: Hiki ke hoʻoheheʻe ʻia i SO(35mg/mL) a i ʻole ethanol (20mg/mL)
ʻAkika helu helu (pKa):7.61±0.20(Wanamua)


Huahana Huahana

Nā ʻike ʻē aʻe

Huahana Huahana

Hoʻolauna Huahana

ʻO Stephania Extract Cepharanthine Powder kahi mea i loaʻa mai nā ʻōpala o ka mea kanu Stephania cephalantha Hayata(Stephania japonica (Thunb.) Miers) a i ʻole Stephania epigaea Lo/ Stephania yunnanensis HSLo. ʻO Cepharanthine kahi huahana kūlohelohe i hoʻokaʻawale ʻia mai kēia mea kanu a ua lilo ia i kumuhana o nā noiʻi like ʻole ma muli o kāna mau waiwai pharmacological. Ua ʻike ʻia e hōʻike i nā hana anti-SARS-CoV-2, e hōʻike ana i ka maikaʻi i ke kāohi ʻana i ka hoʻonui ʻana o ka maʻi. Eia hou, ua hōʻike ʻo Cepharanthine i ka hiki ke hoʻohuli i ka P-glycoprotein (P-gp) -mediated multidrug resistance i kekahi mau cell a hoʻonui i ka naʻau o nā mea anticancer i nā hoʻohālike hoʻokolohua. Eia kekahi, ua hōʻike ʻia i nā hopena inhibitory ma ke akepaʻa cytochrome P450 enzymes CYP3A4, CYP2E1, a me CYP2C9, a pili pū me nā antitumor, anti-inflammatory, a me nā hopena antinociceptive.
I ka hōʻuluʻulu ʻana, ʻo Stephania Extract Cepharanthine Powder he ʻano pauka o ka huahana maoli ʻo Cepharanthine i loaʻa mai ka mea kanu Stephania cephalantha, i hōʻike i ka hiki i nā noi pharmacological like ʻole.

Hōʻike (COA)

Huahana ʻO Cepharanthine
CAS 481-49-2
Hoʻāʻo 80%~99%
Ka nana aku Pauda keʻokeʻo
Hoʻopili 1KG/ʻEke Foil
'ikamu Hōʻike
Ka nana aku ʻeleʻele keʻokeʻo hina, ʻala kū ʻole, hygroscopic loa
ʻIkepili TLC: ʻO ka hoʻonā maʻamau a me ka hoʻonā hoʻāʻo i kahi hoʻokahi, RF
ʻIke (Ke kumu maloʻo) 98.0%--102.0%
Optical kikoʻī -2.4°~ -2.8°
PH 4.5-7.0
Nā Metala Kaumaha (Me Pb) ≤10ppm
As ≤1ppm
Pb ≤0.5ppm
Cd ≤1ppm
Hg ≤0.1ppm
Mea pili ʻAʻole ʻoi aku ka nui o kahi kiko ma mua o ka wahi hoʻonā maʻamau
Ke koena solvent <0.5%
Waiwai <2%

Nā hiʻohiʻona huahana

ʻO Stephania Extract Cepharanthine Powder kahi huahana kūlohelohe i loaʻa mai ka mea kanu Stephania cephalantha Hayata. Ua loaʻa iā ia he mau waiwai pharmacological, e like me:
1. Nā hana Anti-SARS-CoV-2
2. Nā hopena inhibitory i ka laha ʻana o ka maʻi viral
3. ʻO ka hoʻihoʻi ʻana o ka P-glycoprotein-mediated multidrug resistance
4. Hoʻonui i ka noʻonoʻo i nā mea anticancer
5. Nā hopena pale i nā enzymes cytochrome P450 ate kanaka CYP3A4, CYP2E1, a me CYP2C9
6. Antitumor, anti-inflammatory, a me nā hopena antinociceptive

He aha ka Biosynthesis o Cepharanthine?

Hoʻomaka ka biosynthesis o cepharanthine ma Stephania me ka condensation o dopamine a me 4-hydroxyphenylacetaldehyde (4-HPAA, 5) ma o norcoclaurine synthase (NCS), e hāʻawi ana i ka norcoclaurine.

He aha ka Solubility o Cepharanthine?

Hiki ke hoʻoheheʻe ʻia ka Cepharanthine i nā mea hoʻoheheʻe kūlohelohe e like me ka ethanol, DMSO, a me ka dimethyl formamide (DMF). ʻO ka solubility o ka cepharanthine i loko o kēia mau mea hoʻoheheʻe ma kahi o 2, 5, a me 10 mg / ml. ʻAʻole hiki ke hoʻoheheʻe ʻia ka Cepharanthine i loko o ka wai.

Nā noi

ʻO nā ʻoihana noi no Stephania Extract Cepharanthine Powder e pili ana i ka Pharmaceutical, Nutraceutical, Biotechnology, a me nā lāʻau lapaʻau, ʻo nā noi nui e like me kēia:
Hiki ke hoʻohana i nā lāʻau antiviral
Loaʻa ma ke ʻano he adjuvant i ka mālama ʻana i ka maʻi kanesa
Hiki ke hoʻohana i nā lāʻau anti-inflammatory
Loaʻa ma ke ʻano he analgesic agent
Hōʻike kēia mau noi i nā hoʻohana like ʻole o Stephania Extract Cepharanthine Powder i nā ʻano therapeutic like ʻole.


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    Hoʻopili ʻia
    * Ka manawa hoʻouna: Ma kahi o 3-5 mau lā hana ma hope o kāu uku.
    * Pūʻolo: I loko o nā pahu fiber me ʻelua ʻeke plastik i loko.
    * Kaumaha ʻupena: 25kgs/pahu, Kaumaha Nui: 28kgs/Drum
    * Ka nui o ka pahu a me ka leo: ID42cm × H52cm, 0.08 m³/ pahu
    * Waihona: Mālama ʻia ma kahi maloʻo a me ka maʻalili, e mālama i ka mālamalama ikaika a me ka wela.
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    Hoʻouna
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    * Hoʻouna kai no ka nui ma luna o 500 kg; a loaʻa ka hoʻouna ea no 50 kg ma luna.
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    Hōʻike
    Ma lalo o 100kg, 3-5 mau lā
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    Ma ke Kai
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