ʻO ka hoʻokaʻawale ʻana o Vinca Rosea Vincristine
ʻO Vinca Rosea Extract ʻO Vincristine e pili ana i ka hui lāʻau lapaʻau ʻo Vincristine, i loaʻa mai ka mea kanu periwinkle (Vinca rosea), i ʻike ʻia hoʻi ʻo Catharanthus roseus, nā maka ʻālohilohi, Cape periwinkle, mea kanu ilina, Madagascar periwinkle, kaikamahine kahiko, pink periwinkle, rose periwinkle, he ʻano mau o ka mea kanu pua i ka ʻohana Apocynaceae.
He alkaloid kūlohelohe ʻo Vincristine a hoʻohana ʻia ia ma ke ʻano he lāʻau lapaʻau chemotherapy e mālama ai i nā ʻano maʻi kanesa like ʻole, me ka leukemia, lymphoma, a me nā puʻupuʻu paʻa. Hana ia ma ka hoʻopilikia ʻana i ka ulu ʻana o nā hunaola kanesa.
| Nā Mea Hana Nui ma ka ʻōlelo Kina | Inoa Pelekania | Helu CAS. | Kaumaha Molekala | Formula Molekala |
| 长春胺 | Vincamine | 1617-90-9 | 354.44 | C21H26N2O3 |
| 脱水长春碱 | ʻAnahydrovinblastine | 38390-45-3 | 792.96 | C46H56N4O8 |
| 異長春花苷內酰胺 | ʻO Strictosamide | 23141-25-5 | 498.53 | C26H30N2O8 |
| 四氢鸭脚木碱 | ʻO Tetrahydroalstonine | 6474-90-4 | 352.43 | C21H24N2O3 |
| 酒石酸长春瑞滨 | ʻO ka Vinorelbine Tartrate | 125317-39-7 | 1079.12 | C45H54N4O8.2(C4H6O6);C |
| 长春瑞滨 | ʻO Vinorelbine | 71486-22-1 | 778.93 | C45H54N4O8 |
| 长春新碱 | ʻO Vinkristine | 57-22-7 | 824.96 | C46H56N4O10 |
| 硫酸长春新碱 | ʻO Vincristine sulfate | 2068-78-2 | 923.04 | C46H58N4O14S |
| 硫酸长春质碱 | ʻO Catharanthine Sulfate | 70674-90-7 | 434.51 | C21H26N2O6S |
| 酒石酸长春质碱 | ʻO ka Catharanthine hemitartrate | 4168-17-6 | 486.51 | C21H24N2O2.C4H6O6 |
| 长春花碱 | ʻO Vinblastine | 865-21-4 | 810.99 | C46H58N4O9 |
| 长春质碱 | ʻO Catharanthine | 2468-21-5 | 336.43 | C21H24N2O2 |
| 文朵灵 | ʻO Vindoline | 2182-14-1 | 456.53 | C25H32N2O6 |
| 硫酸长春碱 | Vinblastine Sulfate | 143-67-9 | 909.05 | C46H60N4O13S |
| β-谷甾醇 | β-Sitosterol | 83-46-5 | 414.71 | C29H50O |
| 菜油甾醇 | ʻO Campesterol | 474-62-4 | 400.68 | C28H48O |
| 齐墩果酸 | ʻAkika Oleanolic | 508-02-1 | 456.7 | C30H48O3 |
| Nā kikoʻī huahana | ||
| Inoa Huahana: | ʻO ka hua waina rosea | |
| Inoa Botanical: | ʻO ka Catharanthus roseus (L.) | |
| ʻĀpana o ka mea kanu | Pua | |
| ʻĀina i hoʻomaka ai: | Kina | |
| Nā mea loiloi | KIKOʻĪ | ʻANO HOʻĀʻO |
| helehelena | Pauka maikaʻi | ʻO ka ʻōnaehana kino |
| Waihoʻoluʻu | Pauka ʻeleʻele lahilahi | ʻIke maka |
| ʻAla a me ka ʻono | ʻAno | ʻO ka ʻōnaehana kino |
| Ka ʻike ʻana | ʻO like me ka laʻana RS | HPTLC |
| Lākiō Hoʻokaʻawale | 4:1~20:1; ʻO Vincristine 98% min | |
| Ka Nānā ʻana i ka Sieve | 100% a hiki i ka 80 mesh | USP39 <786> |
| Pohō ma ka maloʻo ʻana | ≤ 5.0% | Eur.Ph.9.0 [2.5.12] |
| Lehu holoʻokoʻa | ≤ 5.0% | Eur.Ph.9.0 [2.4.16] |
| Ke kēpau (Pb) | ≤ 3.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| ʻArsenic (As) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Cadmium (Cd) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Mercury (Hg) | ≤ 0.1 mg/kg -Reg.EC629/2008 | Eur.Ph.9.0<2.2.58>ICP-MS |
| Metala kaumaha | ≤ 10.0 mg/kg | Eur.Ph.9.0<2.4.8> |
| Nā koena o nā mea hoʻoheheʻe | E kūlike me Eur.ph. 9.0 <5,4> a me EC European Directive 2009/32 | Eur.Ph.9.0<2.4.24> |
| Nā koena o nā pesticides | Nā Rula Hoʻohālikelike (EC) No.396/2005 me nā annexes a me nā hoʻopou hou ʻana Reg.2008/839/CE | Chromatography Kinoea |
| Nā bacteria aerobic (TAMC) | ≤10000 cfu/g | USP39 <61> |
| Mea Hū/ʻŌpala (TAMC) | ≤1000 cfu/g | USP39 <61> |
| ʻO ka Escherichia coli: | ʻAʻohe i loko o 1g | USP39 <62> |
| Nā ʻano Salmonella: | ʻAʻohe i loko o 25g | USP39 <62> |
| ʻO Staphylococcus aureus: | ʻAʻohe i loko o 1g | |
| ʻO Listeria Monocytogenens | ʻAʻohe i loko o 25g | |
| Nā Aflatoxins B1 | ≤ 5 ppb -Reg.EC 1881/2006 | USP39 <62> |
| Nā Aflatoxins ∑ B1, B2, G1, G2 | ≤ 10 ppb -Reg.EC 1881/2006 | USP39 <62> |
ʻO nā hiʻohiʻona huahana o Vinca Rosea Extract Vincristine e komo pū paha me:
Maʻemaʻe kiʻekiʻe:ʻO ka maʻamau, he kiʻekiʻe ka maʻemaʻe o nā huahana Vincristine a kūlike me nā kūlana koʻikoʻi no ka hana ʻana i nā lāʻau lapaʻau e hōʻoia i ka maʻemaʻe a me ke kūpaʻa o ka lāʻau.
Ka hiki ke hahai ʻia ke kumu:Hoʻokaʻawale pinepine ʻia ʻo Vincristine mai ka mea kanu Catharanthus roseus. Hiki ke hahai ʻia kāna kaʻina hana a kūlike me nā kikoʻī o ka hōʻiliʻili ʻana a me ka hana ʻana o nā mea lāʻau lapaʻau botanical.
Paʻa kemika:Ma ke ʻano he hui alkaloid, loaʻa i ka vincristine ke kūpaʻa kemika maikaʻi a kūpono no ka hana lāʻau lapaʻau a me ka mālama ʻana i ka wā lōʻihi.
Hana kū'ē i ka puʻupuʻu:Ma ke ʻano he lāʻau anti-tumor, loaʻa i ka vincristine ka hana o ke kāohi ʻana i ka ulu ʻana a me ka laha ʻana o nā cell tumor a kūpono ia no ka mālama ʻana i nā ʻano maʻi kanesa like ʻole.
Hōʻoia lapaʻau:Ua hōʻoia ʻia ʻo Vincristine ma ke ʻano lapaʻau a ua hoʻohana nui ʻia i ka hana lapaʻau, me ke kākoʻo ʻikepili pharmacological hilinaʻi a me nā hopena lapaʻau.
Hōʻike kēia mau ʻano huahana i ka maikaʻi, ka hana, a me ka waiwai lapaʻau o vincristine ma ke ʻano he lāʻau lapaʻau koʻikoʻi anti-cancer.
ʻO Vinca Rosea Extract ʻIke nui ʻia ʻo Vincristine no kāna mau noi lāʻau lapaʻau i ka mālama ʻana i ka maʻi kanesa a ʻaʻole pili pinepine ʻia me nā pono olakino pololei no ka hoʻohana ʻana o ka mea kūʻai aku. ʻO Vincristine, i loaʻa mai ka mea kanu Vinca rosea, he lāʻau lapaʻau chemotherapy ikaika i hoʻohana ʻia e mālama i nā ʻano maʻi kanesa like ʻole, me ka leukemia, lymphoma, a me nā puʻupuʻu paʻa. Hana ia ma ke keakea ʻana i ka ulu ʻana o nā hunaola kanesa.
He mea nui e hoʻomaopopo he lāʻau lapaʻau i kauoha ʻia ʻo Vincristine i mālama ʻia ma lalo o ka nānā ʻana o nā loea mālama ola kino, a pili kona hoʻohana ʻana me nā hopena ʻaoʻao a me nā pilikia. No laila, ʻaʻole ia e kūʻai pinepine ʻia a hoʻopau ʻia paha no kona mau pono olakino ma waho o nā wahi lapaʻau.
ʻO nā noi kikoʻī o ka Vinca Rosea Extract Vincristine e komo pū me:
Ka Lapaʻau ʻana i ka Maʻi ʻAʻai:Hoʻohana nui ʻia ʻo Vincristine i ka mālama ʻana i nā ʻano maʻi kanesa like ʻole, me ka leukemia, lymphoma, a me nā puʻupuʻu paʻa. Hoʻokele ʻia ia ma ke ʻano he ʻāpana o nā regimen chemotherapy e kāohi i ka ulu ʻana o nā hunaola kanesa.
Noiʻi lāʻau lapaʻau:Hoʻohana ʻia ka ʻāpana i ka noiʻi lāʻau lapaʻau no ka hoʻomohala ʻana i nā lāʻau lapaʻau hou no ka maʻi kanesa a no ke aʻo ʻana i kona ʻano hana.
Kemika Lapaʻau:He mea waiwai nui ʻo Vincristine ma ke kahua o ka kemika lāʻau lapaʻau, e kōkua ana i ka hoʻomohala ʻana i nā lāʻau lapaʻau hou a me nā mea hoʻōla.
ʻO ka ʻenehana bio:Hiki ke hoʻohana ʻia ka mea i unuhi ʻia i nā noi biotechnological, e like me ka hana ʻana o nā ʻano hana anticancer a me nā ʻōnaehana lawe lāʻau.
Nā Hoʻokolohua Lapaʻau:Ke komo nei ʻo Vincristine i nā hoʻokolohua lapaʻau e ʻimi i kona pono i ka mālama ʻana i nā ʻano maʻi kanesa like ʻole a e noiʻi i nā noi kūpono i nā kūlana olakino ʻē aʻe.
Ka Hoʻomākaukau ʻana i nā Lāʻau Lapaʻau:Hoʻohana ʻia ka ʻāpana i ka hana ʻana o nā huahana lāʻau lapaʻau, me nā hoʻonā injectable a me nā ʻano lāʻau ʻē aʻe no ka mālama ʻana i ka maʻi kanesa.
Hōʻike kēia mau noi i nā hoʻohana like ʻole o Vinca Rosea Extract Vincristine i ka mālama ʻana i ka maʻi kanesa, ka noiʻi lāʻau lapaʻau, a me ka hoʻomohala ʻana i nā lāʻau.
He lāʻau lapaʻau chemotherapy ikaika ʻo Vincristine, a hiki ke pili i kona hoʻohana ʻana me kekahi mau hopena ʻaoʻao. ʻO kekahi o nā hopena ʻaoʻao o ka pauka Vincristine e komo pū me:
ʻO ka maʻi lolo:Hiki i ka Vincristine ke hōʻino i ka ʻōnaehana nerve peripheral, e alakaʻi ana i nā hōʻailona e like me ka numbness, tingling, a me ka nāwaliwali ma nā lālā.
Nā hopena o ka ʻōpū:ʻO nā hopena ʻaoʻao maʻamau o ka gastrointestinal e komo pū me ka nausea, ka luaʻi ʻana, ka constipation, a me ka ʻeha o ka ʻōpū.
Ka Hoʻopau ʻana i ka Iwi Momona:Hiki i ka Vincristine ke kāohi i ka iwi ʻiʻo, e alakaʻi ana i ka emi ʻana o ka hana ʻana o nā hunaola koko, kahi e hopena ai i ka anemia, ka hoʻonui ʻia o ka maʻalahi i nā maʻi, a me nā ʻano kahe koko.
Ka Pohō Lauoho:Hiki i kekahi poʻe ke loaʻa i ka pohō lauoho a i ʻole ka lahilahi o ka lauoho ma muli o ka mālama ʻana iā Vincristine.
ʻEha ʻāwae:Hiki iā Vincristine ke hana i kahi ʻano ʻeha i ʻike ʻia ʻo "vincristine-induced neuropathy-acute-onset," i hōʻike ʻia e ka ʻeha ʻāʻī a me ka paʻakikī i ka moni ʻana.
Nā hopena ʻē aʻe e hiki ai:ʻO nā hopena ʻaoʻao ʻē aʻe e pili ana i ka nāwaliwali o nā ʻiʻo, nā loli i ke koko, a me nā hopena allergies.
He mea nui e hoʻomaopopo ʻaʻole i piha ka papa inoa ma luna, a pono e nānā pono nā loea olakino i nā poʻe e loaʻa ana iā Vincristine no kekahi mau hopena ʻaoʻao. Hiki ke ʻokoʻa nā hopena ʻaoʻao kikoʻī a me ko lākou koʻikoʻi mai kēlā kanaka a kēia kanaka. Pono nā mea maʻi e kūkākūkā i nā hopena ʻaoʻao a me nā hopohopo me kā lākou mea mālama ola ma mua o ka hoʻomaka ʻana i ka mālama ʻana iā Vincristine.
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